Hemochromatosis or iron overload is a condition cause by the accumulation of excessive iron in the body. This causes iron to accumulate in various organs, especially joints, liver, pancreas, and heart. This can cause serious health problems such as liver disease, heart disease, diabetes. And can damage or stop working, leading to death.
The most common cause of iron overload is excessive blood transfusions. Which is found in anemic patients who need frequent blood transfusions because a bag of blood contains 100-200 times more iron than food. For people who do not receive blood frequently but are at risk of iron overload. The most common genetic disease in Thais is thalassemia, which is a common genetic disease in Thais.
They have abnormal hemoglobin, a component of red blood cells, which makes red blood cell production in the bone marrow inefficient. Red blood cells break down faster and the intestines absorb iron abnormally. This can cause iron overload even without frequent blood transfusions. Other causes include genetic diseases that increase iron absorption from the intestines, such as Hereditary hemochromatosis (HH), chronic hepatitis, alcoholic liver disease, UFABET and fatty hepatitis. Which cause the liver to store iron abnormally and release more ferritin, causing iron overload in other organs. Other less common causes include receiving too much iron vitamins and minerals.
Too much iron can cause a number of symptoms:
- Early symptoms: fatigue, joint pain, abdominal pain, and changes in skin color.
- Long-term complications: If left untreated, it can lead to liver damage, heart problems, diabetes, and hormone imbalances.
Careful management of iron intake is important:
- Dietary management: Consider iron-rich foods and supplements.
- Regular health checks: Regular blood tests can help check your iron levels.
Treatment of iron overload is by giving oral iron chelators such as Deferiprone and Deferasirox. These drugs bind iron to a form that can be excret in the feces and urine. For those who do not have anemia and are treat by phlebotomy. They should take care of themselves by not taking vitamins or supplements that contain iron. They should be careful when using substances that affect the liver, such as alcohol. The treatment focuses on removing excess iron from the body to prevent permanent damage to the organs. Treatment can only be supportive and treat the symptoms, which are chronic and can lead to loss of life.
Understanding the risks of iron overload is just as important as recognizing the benefits of iron. By staying informed and tracking your iron levels. You can protect yourself from the potential risks of iron overload and maintain optimal health.